UJI AKTIVITAS ANTIKOLESTEROL EKSTRAK BATANG Uncaria cordata (Lour.) Merr. TERHADAP KADAR KOLESTEROL TOTAL MENCIT JANTAN (Mus musculus)

نویسندگان

چکیده

The aim of this study was to determine the anticholesterol activity stem extract Uncaria cordata (Lour.) Merr. on total cholesterol levels in male mice (Mus musculus). Before carrying out test, phytochemical tests were carried content secondary metabolites stems. Furthermore, test vivo using mice, induced by high-fat diet (PTL) form beef brain, quail egg yolk and propylthiouracil increase until they experienced hypercholesterolemia, then plant extracts see activity. Cholesterol measured a glucometer (Autocheck). Phytochemical results showed flavonoids, saponins, alkaloids, tannins terpenoids. anti-cholesterol that there as indicated decrease with hypercholesterolemia. A 11.45% at dose 5.3 mg/30grW; 12.89% 10.2mg/30grW 21.05% 21.2mg/30grW.
 Key words : Anticholesterol, Merr., Hypercholesterolemia

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ژورنال

عنوان ژورنال: Alotrop: Jurnal Pendidikan dan Ilmu Kimia

سال: 2023

ISSN: ['2252-8075', '2615-2819']

DOI: https://doi.org/10.33369/alo.v7i1.28163